Our Ideal Candidate:

You are an experienced discovery biologist with a passion for drug discovery and a proven record of supporting projects from the bench through the design and generation of robust, decision-making data packages addressing key project-related questions. You have experience with routine molecular and cell biology approaches including high-throughput plate-based cellular assays, cell line engineering (e.g. CRISPR/RNAi, lentiviral transductions, plasmid cloning), qPCR, and western blotting. You thrive in a highly collaborative, fast-paced, and multidisciplinary research environment.

Responsibilities: 

• Drive projects from the earliest stages to clinical development through strategic prioritization of parallel efforts and technical execution of necessary experiments.
• Lead the development and execution of project-specific cellular assays to define target mechanisms of action, assess markers of pharmacodynamic response, and identify relevant patient populations.
• Collaborate with interdisciplinary teams to advance molecular glue degradation programs from early hit validation through hit-to-lead campaigns and lead optimization.
• Establish effective screening funnels to support SAR advancement through the design, development, and execution of cellular and/or biochemical assays.
• Actively participate in new target nomination/identification that leverages unique aspects of the molecular glue degrader modality.
• Proactively integrate new information from literature into the overall project strategy.
• Communicate science and strategy effectively in a variety of internal and external settings

Required Qualifications:

• PhD or MD/PhD in Molecular Biology, Pharmacology, or a relevant biological science
• 4+ years of relevant industry experience in a pharmaceutical/biotech environment
• Demonstrated experience advancing preclinical drug discovery efforts including evaluation of novel targets/pathways for therapeutic potential or characterization of molecules in relevant disease models
• Experience with cell line engineering including lentiviral transduction, CRISPR, and RNAi
• Experience with routine molecular biology assays including western blotting and PCR
• Excellent verbal and written communication and interpersonal skills
• Desire and capacity to participate in a dynamic and fast-paced research setting
• Desire and capacity to work collaboratively as part of a multidisciplinary team

Preferred Qualifications:

• Experience with targeted protein degradation is highly desirable
• Experience working with large datasets is a plus
• Proficiency with plasmid cloning

What we offer: 

• Industry competitive compensation
• Annual target bonus
• Stock options
• 401K plan
• Career advancement opportunities
• Monthly town halls to share business and scientific updates

Work Hard, Stay Well 

• Comprehensive medical, dental, and vision plans for employees and their dependents
• Health and Dependent Care FSA and HSA Plan with monthly Neomorph contribution
• Employee Assistance Program
• 10 holidays + Winter Shutdown + 3 weeks of vacation time with additional accruals after 2nd year of employment, separate sick leave.
• Supplemental pay for Pregnancy Disability Leave
• Paid Parental Leave for employees with a newborn child or a child placed with them for adoption or foster care

Lifestyle

• Casual work environment
• Volunteer days off each year to spend time contributing to causes you care about
• Flexible work schedule
• Access to onsite gym
• Onsite space to store your bicycle (or surfboard) 

Have Fun! 

We believe in work/life balance and Fun is at the core of our Core Values.  In addition to department and company happy hours, we have regular company-wide and department lunches and social events (ie Padres games, summer picnic, holiday party, bring your kids to work day).

About Us: 

Neomorph is a venture-backed biotechnology company solving critical problems in human health through the discovery and development of innovative new medicines against ‘undruggable targets’. Our team is comprised of industry leading experts in protein degradation and molecular glues who have a track record of ground-breaking discoveries in the field. We are committed to leadership in advancing the science and technology of molecular glue drug discovery, while prosecuting a pipeline of projects through clinical development. Our patient-first, science-driven approach is complemented by our dedication to a supportive and collaborative work environment. 

Neomorph is headquartered in San Diego, California, and has a key collaboration with the Center for Protein Degradation at the Dana-Farber Cancer Institute. 

Neomorph is committed to pursuing and hiring a diverse workforce and is proud to be an equal-opportunity employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of any characteristic protected by applicable federal, state, or local law.

Notice to agencies: Neomorph will not accept unsolicited assistance from recruiting/search agencies for this employment opportunity. Please, no phone calls or emails. All resumes submitted by recruiting or search agencies to any employee at Neomorph via email, the Internet or in any form and/or method without a valid written search/recruitment agreement in place for this position will be deemed the sole property of Neomorph. No fee will be paid in the event the candidate is hired by Neomorph as a result of the referral or through other means.