Chief Medical Officer

San Diego, CA

Neomorph is a venture backed biotechnology company solving critical problems in human health through the discovery and development of innovative new medicines against ‘undruggable targets’. Our team is comprised of industry leading experts in protein degradation and molecular glues who have a track record of ground-breaking discoveries in the field. We are committed to leadership in advancing the science and technology of molecular glue drug discovery, while prosecuting a pipeline of projects through clinical development. Our patient-first, science-driven approach is complemented by our dedication to a supportive and collaborative work environment.

Neomorph is headquartered in San Diego, California, and has a key collaboration with the Center for Protein Degradation at the Dana-Farber Cancer Institute.

The Chief Medical Officer (CMO) is the chief architect of the clinical development and product registration road maps, bridging basic science with clinical science, setting the development and regulatory strategy. The CMO will lead, manage, and direct the Neomorph’s pre-clinical and clinical development programs, medical science, and regulatory affairs registration pathways. This position will be responsible for providing leadership, strategic insight, and operational expertise for Neomorph’s research, development, medical and regulatory affairs functions. 


  • Leadership and management of the full life cycle of pre-clinical and clinical development including but not limited to Translational Biology, Clinical Operations, Medical Affairs, Biostatistics and Pharmacovigilance, in addition to Regulatory Affairs & Quality.
  • Steward early discovery, translation medicine and early development strategies to identify and advance new drug targets and bridge preclinical and early clinical phases to elevate probability of success and the speed in which portfolio assets are advanced to late-stage phases.
  • Leadership on clinical content and development strategy on regulatory submissions and interactions.
  • Leadership of all Regulatory Affairs related activities supporting submissions and CMC and other regulated activities.
  • Partner with HR to recruit and develop talent to build highly capable Pre-clinical, CMC, Development, Quality, Pharmacovigilance and Regulatory Affairs organizations.
  • Serve as the clinical spokesperson interfacing with external stakeholders including KOLs, regulatory authorities, advisory board members, clinical research investigators and collaborators.
  • Plan and manage overall budgets.
  • Participate on pre-clinical, medical and clinical, and product registration committees as appropriate.
  • Promote and integrate industry best practices that fit well with the Company’s operating culture.
  • Promote a highly interconnected discovery and clinical research operating culture.
  • Establish and oversee compliance to SOPs and work practices governing all phases of the discovery and clinical research process.
  • Ensure that discovery and clinical research pathways are developed to support registration roadmap with full understanding of the risks and opportunities.
  • Promote a high performance – results oriented collaborative and nimble work culture.
  • Support Business Development activities specifically related to clinical programs analysis and due diligence.
  • Partner with discovery teams to inform and prioritize early portfolio decisions.



  • Board certified MD or MD/PhD required. Board certification in Oncology preferred.
  • Minimum of 15 years of drug development leadership with a track record in oncology.
  • Track record of advancing to PoC through Ph. II/III stage therapeutic candidates through the clinic to regulatory submission and approvals, ideally with a demonstrated track record of successful interactions with regulatory agencies.
  • Track record of strong leadership across the spectrum of clinical and medical activities.
  • Established reputation as a respected medical director and/or a practitioner, along with well-developed relationships and network amongst thought leaders in oncology.

Neomorph provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.